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2026
Negrón Research Group Research Featured by WAPA TV Following Nanomaterials Publication (May 19, 2026)
Research conducted by the Negrón Research Group at the University of Puerto Rico at Cayey was recently featured by WAPA TV following the publication of our scientific article in the journal Nanomaterials.
The television and digital news report highlighted the development of modular Bis-MPA dendron systems capable of self-assembling into supramolecular particles with tunable morphologies and selective biological activity. The study explored how structural modifications influence particle formation, physicochemical properties, and interactions with healthy and cancerous cells, providing important insights into the future development of nanostructured materials for biomedical applications.
The project represents several years of research carried out at the University of Puerto Rico at Cayey and involved the contributions of undergraduate researchers Alondra López-Colón, Waldemar A. Rivera Burgos, Christian A. Morales Borges, Ansé E. Santiago Figueroa, and Jean M. Rodríguez Rivera, whose dedication and scientific contributions were instrumental to the success of the study.
The research was conducted through an interdisciplinary collaboration involving faculty and researchers from multiple campuses within the University of Puerto Rico system. We gratefully acknowledge the contributions of Dr. Clara Camacho-Mercado (University of Puerto Rico, Río Piedras), Dr. Yancy Ferrer Acosta (University of Puerto Rico, Medical Sciences Campus), and Mr. Bismark Madera, whose expertise in biological evaluation, cancer biology, microscopy, and image analysis significantly strengthened the project and expanded the scope of the investigation.
The media coverage emphasized the importance of undergraduate research experiences and demonstrated how students at UPR Cayey actively contribute to peer-reviewed scientific publications and impactful scientific discoveries. Beyond its scientific significance, the project serves as an example of how undergraduate students can participate in high-level research while developing the skills necessary for future careers in science, medicine, and graduate education.
This recognition highlights the growing visibility of research conducted within the Department of Chemistry at UPR Cayey and demonstrates the impact that undergraduate research can have both within the scientific community and through public outreach efforts.
We thank all students, collaborators, mentors, and institutional partners whose dedication made this achievement possible. We are also grateful to WAPA TV for helping communicate the importance of scientific research and higher education in Puerto Rico.
Original news article:
https://wapa.tv/noticias/ciencia/investigadores-upr-cayey-trabajan-con-mol-culas-que-cambiar-an-tratamiento-c-ncer/article_c3f2cbe8-acf5-4b48-9466-c0a0cb76d0ef.html: Negrón Research LabResearch Published in Nanomaterials Featured by El Nuevo Día (May 17, 2026)
The Negrón Research Group was recently featured in Puerto Rico’s leading newspaper, El Nuevo Día, following the publication of our research article in the journal Nanomaterials. The article highlighted the work of undergraduate researchers from the Department of Chemistry at the University of Puerto Rico at Cayey and the potential biomedical impact of our findings.
The published study, “Self-Assembly of Modular Bis-MPA Dendrons into Colloidal Particles with Tunable Morphology and Selective Cytotoxicity”, investigated the design and self-assembly of modular dendron systems capable of forming colloidal supramolecular particles with controllable morphologies and selective biological activity. The research explored how molecular structure influences particle formation, physicochemical properties, and interactions with healthy and cancerous cells.
As discussed in the newspaper feature, the developed particles demonstrated promising behavior in preliminary biological studies, including selective interactions with tumor cells and potential future applications in drug delivery and cancer research. While additional studies are necessary before therapeutic applications can be considered, the work establishes an important foundation for future investigations involving supramolecular nanomaterials and biomedical systems.
The project was carried out through a collaborative effort involving undergraduate researchers from UPR Cayey together with collaborators from the University of Puerto Rico at Río Piedras and the University of Puerto Rico Medical Sciences Campus. The study highlights the impact that undergraduate research experiences can have in producing peer-reviewed scientific publications and interdisciplinary scientific collaborations.
The students recognized in the newspaper article include:
- Alondra López-Colón
- Waldemar A. Rivera Burgos
- Christian Morales Borges
- Ansé E. Santiago Figueroa
- Jean M. Rodríguez Rivera
This achievement was also made possible through valuable interdisciplinary collaborations. We gratefully acknowledge the contributions of Dr. Clara Camacho-Mercado (University of Puerto Rico, Río Piedras Campus), Dr. Yancy Ferrer Acosta (University of Puerto Rico, Medical Sciences Campus), and Lic. Bismark Madera (Molecular Sciences Research Center), whose expertise and support in biological studies, microscopy, and cellular evaluation were instrumental in advancing this research. Their collaboration strengthened the scientific scope of the project and contributed significantly to the successful publication of these findings.
Their contributions played an important role in the development of the project and demonstrate the strong research culture fostered within the Department of Chemistry at UPR Cayey.
We are grateful to all student researchers, collaborators, mentors, and institutional partners who contributed to this work and helped make this achievement possible.
https://www.elnuevodia.com/ciencia-ambiente/otros/notas/investigadores-de-la-upr-detectan-moleculas-que-podrian-revolucionar-el-tratamiento-del-cancer-cerebral/: Negrón Research LabUndergraduate Research Presentations in QUIM 4999 Showcase Student Research Projects (May 14, 2026)
The Negrón Research Group proudly participated in the QUIM 4999 Undergraduate Research Presentations held on May 14, 2026, at the Department of Chemistry of the University of Puerto Rico at Cayey.
During this event, undergraduate researchers presented the results of their independent research projects conducted throughout the academic year. The presentations highlighted a wide range of topics including supramolecular chemistry, drug delivery, environmental remediation, polymer science, and computational chemistry.
Students from the Negrón Research Group delivered the following presentations:
- Luis D. Garay Colón — Correlation of Hydrophobicity (Log P) and Drug–MDP Interactions: Implications for Statin-Based Therapeutics in Ischemic Stroke Models
- Victor Y. Barreto González — Alginate–MDP Nanocomposites for the Removal of Pyrene-Derived Organic Pollutants from Water
- Kyanelisse M. Flores Morales — Versatile 5-Methylvalerate MDP Platforms for the Encapsulation of Biomacromolecules and Hydrophobic Drugs Including Doxorubicin and Tamoxifen
- Emmanuel Cruz Matos — MDP-pNIPAM Nanocomposites for Controlled Uptake of Rhodamine B in Environmental Remediation Applications
The event provided students with an opportunity to communicate their scientific findings, strengthen their presentation skills, and engage in scientific discussion with faculty members and fellow students.
Research experiences such as QUIM 4999 play a critical role in preparing undergraduate students for graduate studies, professional careers, and future scientific leadership.
As part of the celebration, members of the research group also recognized Waldemar A. Rivera Burgos, an important member of the laboratory, and celebrated his birthday following the presentations. Waldemar has contributed significantly to several research initiatives of the group and continues to be an active participant in the laboratory’s research activities.
Congratulations to all students for their dedication, hard work, and successful presentations.
Undergraduate Researchers Selected for Competitive Summer Internships (April 16, 2026)
The Negrón Research Group is proud to announce that three of our undergraduate researchers have been selected to participate in highly competitive summer research internships for 2026. These opportunities reflect their dedication, scientific curiosity, and commitment to advancing their training in chemistry and related fields.
These achievements represent a significant milestone for our students and our research program. We are extremely proud of their accomplishments and look forward to seeing the impact of their summer research experiences.
Negrón Research Group Students Recognized at UPR Cayey Honor Roll Ceremony
The Negrón Research Group proudly congratulates Emmanuel Cruz Matos, Waldemar A. Rivera Burgos, and Kyanelisse M. Flores Morales for their recognition during the University of Puerto Rico at Cayey Honor Roll Ceremony held on April 15, 2026.
These students were recognized for their outstanding academic performance and commitment to excellence throughout their undergraduate studies while actively participating in research activities within the Department of Chemistry.
Balancing coursework, laboratory research, scientific presentations, and academic responsibilities requires dedication and perseverance. Their achievements reflect the strong commitment to academic and professional development that characterizes members of the Negrón Research Group.
A special recognition was also presented to Waldemar A. Rivera Burgos for his exceptional academic consistency, having earned Honor Roll distinction during every academic year since entering the University of Puerto Rico at Cayey. This accomplishment reflects years of sustained excellence, discipline, and commitment to academic success.
The accomplishments of Emmanuel, Waldemar, and Kyanelisse demonstrate that excellence in undergraduate research can go hand in hand with outstanding academic performance.
We congratulate these students on this well-deserved recognition and look forward to their continued success in their future academic and professional careers.
Thanks Ciencia PR for sharing our recently manuscript News!!! (April 13, 2026)
We want also to thanks the Institute of Interdisciplinary Research and ACS Student Chapter (Círculo de Química) from UPR Cayey for also sharing our Manuscript News!!
New Publication in Nanomaterials: Modular Dendron Particles (March 27, 2026)
We are pleased to announce our latest publication in the journal Nanomaterials, where we report the development of modular dendron-based particles derived from bis-MPA.
These supramolecular systems demonstrate the ability to self-assemble in aqueous media and form well-defined nanostructures with potential applications in drug delivery.
Notably, these particles show promising anticancer activity and can act as structure-directing agents for the formation of complex flower-like morphologies.
This work highlights the versatility of modular dendron systems in tuning physicochemical and biological properties for biomedical applications.
2025
We are pleased to announce our latest publication in ACS Applied Bio Materials, where we report the development and biological evaluation of guanosine-based supramolecular particles for drug and gene delivery applications. (June 19, 2025)
In this work, we investigate a unique class of colloidal systems known as supramolecular hacky sacks (SHS), which self-assemble from guanosine derivatives and form highly tunable nanostructures in aqueous media.
These particles demonstrate structure-dependent cellular uptake, with specific compositions showing selective internalization and intracellular trafficking in neuroblastoma and HEK cells.
Importantly, SHS particles function as effective delivery platforms for both small molecules and genetic material. We show successful encapsulation and intracellular release of doxorubicin, leading to enhanced cytotoxic effects, as well as plasmid transfection with sustained protein expression.
These findings highlight the potential of supramolecular systems as modular and biocompatible platforms for biomedical applications, bridging the gap between traditional polymer-based carriers and small-molecule precision.
The figure above illustrates the hierarchical self-assembly process from molecular building blocks to microscale particles, as well as their application in drug and gene delivery.
🔗 Read the full article:
https://doi.org/10.1021/acsabm.5c00201
- Undergraduate Research Presentations in QUIM 4999 (December 4, 2025)
On December 4, 2025, undergraduate researchers from the Negrón Research Group presented their research projects as part of the seminar component of QUIM 4999 – Undergraduate Research in Chemistry at the University of Puerto Rico at Cayey.
This seminar provided students with an opportunity to present their research findings, strengthen their scientific communication skills, and engage in academic discussion within the department.
The following students from the research group participated in this activity:
Kyanelisse M. Flores Morales
Design and characterization of Hemoglobin-Modular dendron particle complex as a convenient strategy to produce synthetic blood
Waldemar A. Rivera Burgos
Encapsulation and quantification of the hydrophobic cancer drug Doxorubicin using tunable modular dendron particles
These presentations reflect the continued development of undergraduate research projects within the group and highlight the integration of teaching and research through structured seminar activities.
QUIM 4999 continues to serve as a key platform for training students in experimental design, data analysis, and scientific communication, preparing them for future research and professional opportunities.
- Student Presentation at PRISM & ACS Junior Technical Meeting (March 26, 2025)
We are pleased to highlight the participation of our undergraduate researcher, Waldemar A. Rivera Burgos, from the Department of Chemistry at the University of Puerto Rico at Cayey, in the 43rd Puerto Rico Interdisciplinary Scientific Meeting (PRISM) and the 58th ACS Junior Technical Meeting.
The presentation took place on March 26, 2025, and showcased research conducted as part of the Negrón Research Group.
Project Title: Synthesis and Characterization of Alginate-Lipid Dendrimer Nanocomposites for the Development of Versatile Nanomaterials for Water Purification
This work focuses on the development of hybrid nanomaterials combining alginate-based systems with lipid dendrimer architectures, aiming to create versatile and efficient platforms for environmental remediation applications, particularly in water purification.
Undergraduate participation in scientific meetings such as PRISM and ACS provides valuable training in research communication and contributes to the development of the next generation of scientists.
This work was conducted under the mentorship of Dr. Luis M. Negrón as part of ongoing research efforts in supramolecular and nanostructured materials.
2024
- Undergraduate Research Presentations in QUIM 4999 (December 12, 2024)
Undergraduate researchers from the Negrón Research Group presented their work as part of the seminar component of QUIM 4999 – Undergraduate Research in Chemistry during the Fall 2024 term at the University of Puerto Rico at Cayey.
These presentations provided students with an opportunity to further develop their research projects, refine their scientific communication skills, and engage in academic discussion within the department.
Waldemar A. Rivera Burgos
Synthesis and Characterization of Alginate Hydrogels for the Production of Lipid Dendrimer Nanocomposites
Cristian A. Morales Borges
Lipid Dendrimer Nanoparticles to Increase Water Solubility of Hydrophobic Cancer Drugs
Yanaidy Pagán Zayas
Structural Study and Absorption Properties of Lipid Dendrimer pNIPAM Nanocomposites
These activities reflect the continuous development of undergraduate research projects within the group, as well as the integration of research and teaching through structured seminar experiences.
QUIM 4999 serves as a key platform for training students in experimental design, data analysis, and scientific presentation, preparing them for future participation in conferences and advanced research opportunities.
- Invited Graduate Seminar at UPR Río Piedras – Department of Chemistry (September 25, 2024)
On September 25, 2024, Dr. Luis M. Negrón delivered an invited seminar at the University of Puerto Rico, Río Piedras Campus, hosted by the Department of Chemistry Graduate Program.
The seminar took place at the College of Natural Sciences (Amphitheatre A-211) and was coordinated by faculty members as part of the graduate seminar series.
Seminar Title: Novel Approaches for the Construction of Lipid Dendrimer Nanoparticles and pNIPAM Hydrogels Used for the Formation of Nanocomposites
During this presentation, ongoing research from the Negrón Research Group was discussed, focusing on the synthesis and self-assembly of lipid dendrimer nanoparticles and their integration into polymeric hydrogel systems for the development of nanocomposite materials.
The seminar highlighted key concepts in supramolecular chemistry, nanotechnology, and stimuli-responsive materials, emphasizing their potential applications in biomedical and advanced materials research.
This invited talk reflects continued collaboration and scientific exchange between UPR-Cayey and UPR-Río Piedras, strengthening interdisciplinary research efforts within the University of Puerto Rico system.
- Participation at ACS Fall Meeting in Denver, Colorado (August 18–22, 2024)
From August 18 to August 22, 2024, Dr. Luis M. Negrón participated in multiple scientific symposia held during the American Chemical Society (ACS) Fall Meeting, hosted at the Colorado Convention Center and the Sheraton Hotel in Denver, Colorado.
As part of this international conference, Dr. Negrón presented research from the Negrón Research Group focused on the design and development of advanced nanostructured materials.
Presentation Title: Design and synthesis of stimuli-responsive cross-linking lipid dendrimer nanoparticles for the construction of pNIPAM hydrogel nanocomposites
The presentation highlighted ongoing efforts in the development of lipid dendrimer-based nanoparticles and their integration into polymeric hydrogel systems to form nanocomposite materials with tunable properties.
This work emphasizes the role of supramolecular and polymer chemistry in understanding molecular interactions within complex matrices and advancing applications in nanomaterials and biomedical systems.
Participation in ACS national meetings provides an important platform for engaging with the broader scientific community, sharing research findings, and establishing collaborations in the field of materials chemistry.
The research presented also outlines future directions, including the development of libraries of lipid dendrimer nanoparticles and further evaluation of nanocomposite systems.
- Alumni Achievement: Jean M. Rodríguez Rivera Joins the Broad Institute of MIT and Harvard (June 26, 2024)
Following his graduation in June 2024, we are proud to highlight the continued success of Jean M. Rodríguez Rivera, a former undergraduate researcher from the Negrón Research Group.
Jean began his professional research career as a Research Associate in the Epigenomics Program at the Broad Institute, one of the leading biomedical research institutions in the world.
He is currently serving as a Broad Biomedical Postbaccalaureate Scholar and has continued his work as a Research Technician at the Ragon Institute, where he is involved in research focused on molecular and cellular interactions relevant to human health and disease.
During his time in the Negrón Research Group, Jean demonstrated strong commitment to research, contributing to projects in nanomaterials and supramolecular chemistry, and developing the skills necessary for success in high-level research environments.
His transition into internationally recognized research institutions highlights the impact of undergraduate research training and the preparation of students for competitive scientific careers.
We are extremely proud of his accomplishments and wish him continued success in his research career.
Congratulations, Jean!
- Alumni Achievement: Ansé E. Santiago Figueroa Accepted as Pharmacy Intern at HCA Westside Hospital (June 26, 2024)
Following his graduation in June 2024, we are proud to share the continued success of Ansé E. Santiago Figueroa, a former undergraduate researcher from the Negrón Research Group.
Ansé has recently been accepted as a Pharmacy Intern at HCA Westside Hospital, where he will continue gaining professional experience in the healthcare field.
During his time in the research group, Ansé demonstrated strong dedication to both academic and laboratory work, contributing to research projects in nanomaterials and lipid dendrimer systems.
His transition into a clinical and professional setting reflects the versatility of his training and the value of undergraduate research in preparing students for careers in science and healthcare.
We are extremely proud of his accomplishments and wish him continued success in this new stage of his professional journey.
Congratulations, Ansé!
- Congratulations to Jean M. Rodríguez Rivera and Ansé E. Santiago Figueroa on Their Graduation and Outstanding Research Award (June 26, 2024)
On June 26, 2024, members of the Negrón Research Group, Jean M. Rodríguez Rivera and Ansé E. Santiago Figueroa, successfully completed their undergraduate studies in Chemistry at the University of Puerto Rico at Cayey.
Throughout their time in the laboratory, both students demonstrated exceptional dedication to research, contributing to projects focused on lipid dendrimer nanoparticles, nanocomposites, and supramolecular systems.
In recognition of their hard work, commitment, and scientific contributions, they were honored by the Negrón Research Laboratory with the Outstanding Research Award.
Their efforts have played an important role in advancing the group’s research in nanomaterials and have helped strengthen the culture of undergraduate research within the department.
We proudly congratulate Jean and Ansé on this important milestone and wish them continued success in their future professional and academic endeavors.
- Invited Seminar at UPR Medical Sciences Campus – School of Pharmacy (May 16, 2024)
On May 16, 2024, Dr. Luis M. Negrón delivered an invited seminar at the University of Puerto Rico – Medical Sciences Campus (RCM), School of Pharmacy, held in Room 311.
This seminar was hosted as part of the PHSC 8102 course and provided an opportunity to present ongoing research efforts from the Negrón Research Group to a multidisciplinary audience in pharmaceutical sciences.
Seminar Title: Novel Approaches for the Construction of Lipid Dendrimer Nanoparticles and pNIPAM Hydrogels Used for the Formation of Nanocomposites for Biomedical Applications
The presentation focused on the design and synthesis of lipid dendrimer-based nanoparticles and their integration into polymeric hydrogel systems to form nanocomposite materials with tunable physicochemical properties.
Key topics included supramolecular self-assembly, stimuli-responsive materials, and the role of molecular interactions in complex nanostructured systems.
This invited seminar highlights ongoing collaborations and research dissemination efforts between the University of Puerto Rico at Cayey and the Medical Sciences Campus, contributing to interdisciplinary exchange in the fields of nanotechnology and biomedical materials.
- Undergraduate Research Seminar Presentations in QUIM 4999 (April 25, 2024)
On April 25, 2024, undergraduate researchers from the Negrón Research Group presented their research projects as part of the seminar component of the course QUIM 4999 – Undergraduate Research in Chemistry at the University of Puerto Rico at Cayey.
The seminar provided a platform for students to communicate their research findings, develop scientific presentation skills, and receive feedback prior to participation in external conferences.
The following students presented their research during this activity:
Ansé E. Santiago Figueroa
Effect of Structural Modifications of the Triazole Group Linker in Lipid Dendrimer Nanoparticles with the Potential to Encapsulate Biomacromolecules
Cristian A. Morales Borges
The Role of Molecular Structure in Lipid Dendrimer Nanoparticles Used for the Encapsulation of Urea
Yanaidy Pagán Zayas
Understanding the Interaction of pNIPAM and Lipid Dendrimer Nanoparticles for the Construction of Hydrogel Nanocomposites
Jean M. Rodríguez Rivera
Development of a Size Tunability Strategy of Lipid Dendrimer Nanoparticles for Cancer Drug Encapsulation and Delivery Applications
These presentations represent the culmination of their research efforts within the course and reflect the integration of hands-on laboratory experience with scientific communication training. Undergraduate research courses such as QUIM 4999 play a critical role in fostering independent thinking, technical skills, and professional development in chemistry students.
- Undergraduate Student Participation at PRISM & ACS Junior Technical Meeting (April 20, 2024)
On April 20, 2024, Dr. Luis M. Negrón attended the 42nd Puerto Rico Interdisciplinary Scientific Meeting (PRISM) and the 57th ACS Junior Technical Meeting (JTM), held at the University of Puerto Rico, Aguadilla Campus.
This event provided an opportunity to support and engage with undergraduate research presentations across multiple disciplines.
Notably, four undergraduate researchers from the Negrón Research Group presented their work during the meeting:
Their participation highlights the group’s commitment to undergraduate research training and the development of scientific communication skills through national-level conferences.
Events such as PRISM and ACS Junior Technical Meetings play a critical role in fostering early research experiences and promoting the next generation of scientists.
2023
- Undergraduate Research Presentations in QUIM 4999 – Fall 2023 (November 30, 2023)
On November 30, 2023, undergraduate students from the Negrón Research Group presented their research projects as part of the QUIM 4999 – Research in Chemistry course at the University of Puerto Rico at Cayey.
The presentations highlighted ongoing efforts in supramolecular chemistry, nanomaterials, and polymer-based systems, with a focus on the design and characterization of advanced functional materials for biomedical and environmental applications.
Among the presenters were:
Yanaidy Pagán Zayas, who presented her project titled
“Understanding the Molecular Organization of pNIPAM Hydrogels for the Preparation of Lipid Dendrimer Nanocomposites.”
Her work focused on the synthesis and structural study of thermoresponsive pNIPAM hydrogels and their interaction with lipid dendrimer nanoparticles to form nanocomposites with tunable properties .
Cristian A. Morales Borges, who presented
“Development of Efficient Synthetic Strategies for the Construction of Lipid Dendrimer Nanoparticles for the Encapsulation of Urea.”
His research explored synthetic methodologies for lipid dendrimer nanoparticles and evaluated their ability to encapsulate small molecules such as urea, demonstrating promising results for controlled release systems .
These presentations reflect the strong commitment of undergraduate students to research and innovation, as well as their ability to integrate concepts from organic chemistry, materials science, and nanotechnology.
Activities such as these play a key role in developing the next generation of scientists by providing hands-on research experience and opportunities to communicate scientific findings.
We congratulate Yanaidy and Cristian for their excellent work and continued contributions to the research group.
- Presentation at ACS 46th Senior Technical Meeting (November 4, 2023)
On November 4, 2023, Dr. Luis M. Negrón delivered a research presentation at the 46th Senior Technical Meeting of the American Chemical Society, held at the Costa Bahía Convention Center in Guayanilla, Puerto Rico.
Presentation Title: Novel Approaches for the Construction of Lipid Dendrimer and pNIPAM/PVA Hydrogels Used for the Formation of Nanocomposites
This presentation highlighted preliminary results from ongoing research focused on the development of nanocomposite hydrogels based on lipid dendrimers and pNIPAM-derived polymer systems.
The work contributes to the broader field of organic materials chemistry, with applications in the design of advanced functional materials for biomedical and environmental use.
Participation in ACS meetings provides an important platform for the dissemination of research findings and engagement with the scientific community.
- Seminar Presentation at UPR Cayey RISE Program (March 29, 2023)
Synthesis and Development of Lipid Dendrimer Nanoparticles and Molecular Imprinting Polymers for Biomedical Applications
This seminar was delivered during the development phase of a research proposal focused on lipid dendrimer-based nanocomposites.
The presentation covered the design, synthesis, and potential applications of dendrimer-based nanostructures and molecularly imprinted polymer systems, with emphasis on their use in biomedical applications.
These activities reflect ongoing efforts to develop innovative supramolecular and polymer-based materials within the research group.
- Faculty Symposium Presentation at UPR Cayey (March 29, 2023)
On the afternoon of March 29, 2023, Dr. Luis M. Negrón participated in the Faculty Symposium on Research, Creative Work, and Community Service at the University of Puerto Rico at Cayey.
During this institutional event, research efforts related to the development of lipid dendrimer-based nanocomposites were presented to the academic community.
This symposium provided an opportunity to share ongoing research initiatives, foster interdisciplinary collaboration, and highlight the integration of research, teaching, and service.
Activities such as these are essential for strengthening the research culture and academic engagement within the university.
2022
- Congratulations to Alondra López-Colón on Her Graduation and Ph.D. Acceptance (June 24, 2022)
We proudly congratulate Alondra López-Colón, a former undergraduate researcher from the Negrón Research Group, on her graduation from the University of Puerto Rico at Cayey in May 2022.
During her time in the research group, Alondra demonstrated outstanding dedication to her academic and research training, contributing to projects in chemistry and developing a strong foundation for advanced studies.
Following her graduation, Alondra was accepted into the Ph.D. program in Chemistry at the University of Minnesota, a highly competitive and internationally recognized research institution.
Notably, she was also awarded a Departmental Fellowship, recognizing her academic excellence and potential for success in graduate research.
Alondra is currently continuing her doctoral training, further advancing her research career in chemistry.
We are extremely proud of her accomplishments and wish her continued success in her Ph.D. journey.
Congratulations, Alondra!
2021
- Postbaccalaureate Intramural Research Training Award – NIH Academic Enrichment Program (NAEP) (June 14, 2021)
Congratulations to our former lab member José González Dalmasy for his well-deserved fellowship in the POSTBAC IRTA from NAEP!!!
- Alumni Achievement: Ariana De Jesús Hernández, M.D. (May 30, 2021)
We are proud to recognize the achievements of Ariana De Jesús Hernández, a former undergraduate researcher from the Negrón Research Group, who graduated in May 2021 from the University of Puerto Rico at Cayey.
During her time in the research group, Ariana demonstrated outstanding dedication to her academic and research development, contributing to projects in chemistry and gaining valuable laboratory experience.
In recognition of her academic excellence, Ariana received an award from the Department of Chemistry at UPR-Cayey.
Following her undergraduate studies, Ariana continued her academic journey in the field of medicine and is currently pursuing her medical training at the University of Puerto Rico Medical Sciences Campus.
We are especially proud to share that she is now part of the Department of Anesthesiology, continuing her professional development in the medical field.
Ariana’s accomplishments reflect the impact of undergraduate research training and the successful transition of students into advanced professional careers.
Congratulations, Ariana — we are very proud of your achievements and wish you continued success in your medical career!
- Negron’s Research Group Outstanding Research Award (May 28, 2021)
Congratulations to our lab member Ariana de Jesús Hernández.
We recognized her effort with our “Outstanding Research Award“, with appreciation for her dedication to research of excellence!!!
- Virtual Presentation for QUIM4999 – Undergraduate Research Symposium (May 19, 2021)
Our students Ariana, Renis and Alondra presented their research progress reports at the QUIM 4999 virtual symposium!
Congratulations in your excellent presentations!!!
- 8th Student Meeting of Research, Creations, and Community Service of the University of Puerto Rico at Cayey (May 18, 2021)
Our research students Renis, Ariana and Alondra presented at the 8th Student Meeting of Research, Creations, and Community Service of UPRC. Congratulations for this great achievment!!!
Renis J. Agosto Nieves
Ariana De Jesús Hernández
Alondra López Colón
- 8th Student Meeting of Research, Creations, and Community service of the University of Puerto Rico at Cayey
Date: May 18, 2021
Our research students will be presenting their projects at the 8th Student Meeting of Research, Creations, and Community service of the UPR Cayey Interdisciplinary Institute.
Registration deadline: May 10, 2021
- 54th ACS Junior Technical Meeting (JTM) & 39th Puerto Rico Interdisciplinary Scientific Meeting (PRISM)
Date: April 24, 2021
Congratulations Ariana, Renis and the other research students from UPR Cayey on their outstanding virtual research presentations at the 54th ACS Junior Technical Meeting!!!
- 1st Puerto Rico IDeA Network of Biomedical Research Excellence Town Hall Meeting
Date: April 16, 2021
Congratulations to Dr. Negrón on his outstanding virtual research presentation at the first Puerto Rico IDeA Network of Biomedical Research Excellence Town Hall Meeting!!!
He was the only researcher from the University of Puerto Rico presenting!! Congratulations for this great achievement!!!!
- Summer Internships 2021: Center of Sustainable Nanotechnology
Alondra got accepted to the Center for Sustainable Nanotechnology’s Summer Undergraduate Research Experience 2021 at the University of Illinois Urbana Champaign. She will work at the Dr. Catherine Murphy’s Research Laboratory. Congratulations for this great achievement!
2020
- ABRCMS 2020: Outstanding ePosters Presentations Awards!!!
Date: November 16, 2020
Congratulations Alondra, Mariela and the students from UPR Cayey on their ABRCMS 2020 Presentations!! Alondra and Mariela WON Outstanding Presentation Awards!!!
- “A Novel Route to Neuroprotection in Chronic Traumatic Brain Injury” – By Edwin Vázquez Rosa, Ph.D.
Date: November 12, 2020
Platform: Zoom Meetings
Hour: 10:30 am
Chronic neurodegeneration, major cause of the long-term disabilities that afflict survivors of traumatic brain injury (TBI) is linked to an increased risk for late-life neurodegenerative disorders, including Alzheimer’s disease, Parkinson’s disease, vascular dementia, and chronic traumatic encephalopathy.
Dr. Vázquez, current researcher from the Louis-Stokes Cleveland VA Medical Center, offered a conference about his research experience in the finding of the restoration of blood-brain barrier (BBB) structure and function by P7C3-A20 when administered 12 months after TBI. This pharmacotherapy was associated with cessation of chronic neurodegeneration and recovery of normal cognitive function, benefits that persisted long after treatment cessation. Pharmacologic renewal of BBB integrity may this provide a new treatment option for patients who have suffered a remote TBI, or other neurological conditions associated with BBB deterioration.
- Our Research work was on the News!!!
Date: October 26, 2020
El Nuevo Día
Noticentro
University of Puerto Rico Magazine
- “The natural compound 4R-cembranoid and memantine share similar cholinergic pathways to induce neuroprotection” – By Yancy Ferrer Acosta, Ph.D.
Date: October 13, 2020
Platform: Zoom Meetings
Hour: 10:30 am
Dr. Ferrer is an expert in neurobiology; she studies the function and regulation of astrocytes in ischemic strokes.
She offered a conference about her research group investigation of the role of astrocytes in the neuroinflammation process. Some of the studies and techniques performed in her laboratory are primary cell cultures of astrocytes, mouse models of ischemic stroke, western blots, ELISA, immunohistochemistry, among other molecular biology techniques.
Currently, Dr. Ferrer is studying the neuroprotective properties of natural compound 4R-cembrenoid for the development of treatments for ischemic strokes.
- ABRCMS 2020: Abstracts accepted for Virtual Experience!!
Date: September 24, 2020
Alondra and Ariana, current research assistants, got accepted to the Annual Biomedical Research Conference for Minority Students 2020 (ABRCMS 2020) to present their research projects.
- “A Novel Approach of Organic Nanomaterials for Current Challenges in Medicine” – By Luis M. Negrón Ríos, Ph.D.
Date: September 10, 2020
Platform: Zoom Meetings
Hour: 10:30 am
Dr. Negrón talked about his research. His interests are the synthesis and study of stimuli-responsive organic molecules called lipid dendrimers that self-assemble in nanoparticles for drug-delivery applications. He is interested in understanding how lipid dendrimers can form these nanoparticles in order to develop a new alternative for therapeutic agents for neurological applications.
His research group apply concepts of organic chemistry (synthesis and characterization), analytical chemistry, nanotechnology, supramolecular chemistry, among other interdisciplinary areas. He is currently working in lipid dendrimer derivatives used for the encapsulation and delivery of drugs that induce neuroplasticity to treat brain strokes.
- PR-LSAMP 2020 Fellowship: Renis and Ariana received PR-SLAMP Award for Academic Year 2020-2021
Date: August 2020
Current research assistants Renis and Ariana received PR-LSAMP Fellowship for their research projects for academic year 2020-2021. Congratulations for this great achievement!
- Research Training Initiative for Student Enhancement (RISE) Program Fellowship: Alondra was accepted to the RISE Research Group Fall 2020 Cohort
Date: August 3, 2020
Alondra, current research assistant that studies the hydrophobic formation of lipid dendrimers nanoparticles used as a potential strategy to encapsulate statins drugs for drug delivery applications, received RISE award for her research project funding during Fall 2020. Congratulations for this great achievement!
- 7th Student Meeting of Research, Creations, and Community Service
Date: June 19, 2020
Hour: 2:00 pm – 3:00 pm
Ariana and Alondra presented their research projects at the 7th Student Meeting of Research, Creations, and Community service of the University of Puerto Rico at Cayey. Excellent work!!!
- Virtual Presentation for QUIM4999 – Undergraduate Research Symposium
Date: May 14, 2020
Platform: Google Meets
Hour: 10:30 am
Congratulations to Ariana, Alondra and all chemistry students that presented their progress reports at the Undergraduate Research Virtual Symposium of the University of Puerto Rico at Cayey.
- Summer Internships 2020: Center for Sustainable Nanotechnology
Date: March 2, 2020
Alondra got accepted to the Center for Sustainable Nanotechnology’s Summer Undergraduate Research Experience at the University of Illinois Urbana Champaign. She will work at the Dr. Catherine Murphy’s Research Laboratory. Congratulations for this great achievement!
- Activity of Professional Development at the University of Puerto Rico at Cayey
Date: February 14, 2020
Hour: 11:00 am
Place: NEC Amphitheater
Professor Negrón gave an oral presentation about his research as a faculty member from the University of Puerto Rico at Cayey. Congratulations on your well-deserved success!
2019
- Presentation for QUIM4999 – Undergraduate Research Symposium
Date: December 10, 2019
Place: 311 MMM
Hour: 10:30 am
The undergraduate students from the chemistry department, Alondra and Ariana, gave oral presentations for the end of semester at the University of Puerto Rico at Cayey. Excellent work!
- Poster presentations at the PR-Neuroscience Symposium
Date: December 7, 2019
The undergraduate students Alondra, José, and Ariana gave poster presentations at the 27th Puerto Rico Neuroscience Conference hosted by ”Universidad Central del Caribe in Bayamón, PR”. Nice work, and best wishes for the next adventure!
- Negron’s Research Laboratory received three grants on Fall 2019!!!
Date: December 2019
Place: University of Puerto Rico at Cayey
Congratulations on your well-deserved success Dr. Negrón!!!
- PR-LSAMP 2019 Fellowship:
Date: September 11, 2019
Ariana received PR-LSAMP Fellowship for their research projects for academic year 2019-2020. Congratulations for this great achievement!
- Fluorescent Light Microscopy Seminar- By Lic. Bismark Madera
Date: February 27, 2019
Hour: 10:30 am
**NEW PLACE**: NEC Amphitheater
Lic. Bismark Madera from the Neuroimaging and Electrophysiology Facility (NIEF) will be offering a fluorescent light microscopy seminar at the University of Puerto Rico at Cayey. Don’t forget to register for this great opportunity!
Link for Registration
Lab Activities
- End of semester laboratory activity
Date: May 28, 2021
Congratulations to our group members for all their hard work and achievements during the semester!! We wish you a great and well-deserved summer vacation!!
- Christmas lunch
Date: December 16, 2019
Negron research group wishes you a merry christmas, and a happy new year! Cheers!
Negrón Research Lab 